Inspired by Yogscast's attempts at a nuclear power station I decided to build a proper one with IC2 and BC.
I decided to do a constantly applied external cooling system as in my mind that's more realistic compared to proper nuclear reactors. It consumes approximately 14 ice/second but the cooling towers have enough stockpiled for more than two hours of continuous use.
Originally I had planned to use a bug in the equivalent exchange mod where you can transmute 2x Glass -> 3x Sand then cycle that around, extracting the spare sand to turn into glass and then transmute 8x Glass into ice. However the amount of ice this reactor used, would have meant i'd have had to have a rather stupidly high number of sand generators.
I did make some prototypes towards this, some screenshots can be found here: http://imgur.com/a/GdFei
Additionally in there is a prototype cooling tower design where I tried to cram as much cooling storage in as possible, but it got a bit messy. The pipework is all fully working in that mess, however I couldn't work out how to have a switch-able redstone power supply to all of the engines.
The saves are available here if anyone is interested: http://www.mediafire.com/?12krpefb76ffka5