2. Ah, interesting... If all the production reactors are in one tower, so you don't need to use furnaces or anything to connect them, that could work very well. Just make sure that you don't wind up dumping things into an ME Interface or something.
Not a problem, as ME Import/Export bus' are not iSided themselves, so Routers don't see them. And using the "Insert Near" functionality of Routers with Machine Identifiers, you can put the Cell-inserting routers on one side, and the Uranium inserting routers on the other side.
Also, if you DON'T put "Bandwidth" upgrades on the router-feeding routers, they will evenly split the items among all the routers.
You know, the easier way would be just to make a video on how it's done. So here's one.