I picked this trick up somewhere else, but if you have a chest before the macerator, have it go from this chest to the macerator and loop back to the chest so that anything the macerator doesn't do fast enough gets recycled back into the chest. You're not connecting the output of the macerator to this, simply looping pipe back to the chest at the input of the macerator.
Now I haven't gotten into efficiency just yet, but you can power upgrades on the macerator to accept 512v + some speed boosts and that shit will plow through a chest in minutes.