Your best option is to do the same as you do in real life:
produce the power at a powerplant, uptransform it to a higher voltage (higher voltage, lower amperage), transport it at that high voltage and at the end where you're using it again, you downtransform it again (lower voltage, higher amperage).
Alternatively you could also place a batbox/cesu/whatever every x blocks, where x needs to be small enough, that the energy loss is less than 1 EU.