Time for some designs!
You can easily design a MOX reactor with the reactor planner for the time being. At 8,496 degrees, the output multiplier is 4.4 with a high degree of precision. So now that MOX runtime is the same as the old value the reactor planner shows for uranium, all that you have to do is build an uranium reactor and then multiply the "Active EU/t" and "Total EU" figures by 4.4 each in order to get the numbers this design would give with MOX in build 297, at that temperature. I cross-tested several designs ingame yesterday, and this method is reliable.
1.) Let's start off with this design. You've seen it all before - it's the reactor I've been running my tests with. It's a reasonably good first MOX reactor because of its very high efficiency, and because it requires only 4 MOX fuel rods - and if you wonder why this is important, you probably haven't tried to produce enough plutonium for that through legit gameplay yet. An uranium reactor with 9 fuel rods would have to complete 12 cycles of 5 hours 33 minutes each in order to provide the plutonium. In other words, you would be waiting for it for a minimum off 66 hours 40 minutes. RL hours, mind - now try doing this in a singleplayer world and get back to me next month. 
Anyway. The downside of the reactor is that it has a running cost, due to the reflectors. You need thick reflectors, and each pair is good for two cycles. If you have the resources lying around, great, go for it. Because of its high efficiency, MOX fuel is much more valid with reflectors than uranium ever was. But eventually you might want to migrate to a better design.
If you want to spend a lot less diamonds at the cost of adding two more chambers and more pure-metal components, you can also build it like so.
Bottomline: 2 chambers, 2 dual fuel rods, 2 reflectors. 352 EU/t, 70.4m EU/cycle, efficiency 17.6 @ 8,496 degrees
2.) Super basic MOX reactor. This design was highly popular before because the location dependant output bug and the heat plating stacking favored it. It's not as good anymore as it used to be in the bugfixed build 297, though. It's main selling point is that it's cheap and compact to set up, but efficiency is lacking.
This base module can be repeated over and over in the same reactor for extra output. Four such modules will fit in a 0-chamber reactor.
Bottomline: 0 chambers, 1-4 dual fuel rods. 88-352 EU/t, 17.6-70.4m EU/cycle, efficiency 8.8 @ 8,496 degrees
3.) The vest pocket reactor. Okay, portability probably isn't really a given when you need special equipment to heat the reactor up, but this sure is one of the most attractive 0-chamber reactors around. Decent efficiency, decent output, decently low on diamond cost.
Bottomline: 0 chambers, 1 quad fuel rod. 264 EU/t, 52.8m EU/cycle, efficiency 13.2 @ 8,496 degrees
4.) The reactor affectionately known as the Z-snap. Probably one of the best beginner MOX reactors around, because you can use the single fuel rods for extra-precise initial heatup without crafting an extra uranium rod that will never be used anywhere else. The major downside is that it needs 6 fuel rods to set up, which are tough to come by initially. Output and efficiency, however, are very impressive for something with zero running cost.
Bottomline: 3 chambers, 2 single + 2 dual fuel rods. 484 EU/t, 96.8m EU/cycle, efficiency 16.13 @ 8,496 degrees
5.) I like to call this one the tsunami, both because of its ripple shape, and because it buries you under a deluge of power. This is what you can expect, roughly, from a high-end MOX reactor with internal cooling. You can start with a smaller reactor when you have just a few fuel rods, and then later when you have enough plutonium to make 8 at once, upgrade to this while reusing pretty much all your components. It'll give you a performance you've never before seen in an internal vent cooled reactor - not even in the legendary age of GregTech hybrid reactors!
Bottomline: 6 chambers, 2 quad fuel rods. 704 EU/t, 140.8m EU/cycle, efficiency 17.6 @ 8,496 degrees
Now I'm eager to see what kind of designs you guys can come up with 